TURMERIC AND COLON CANCER
What is Colon Cancer
In colon cancer there is uncontrolled division of abnormal cells in the rectum or colon or malignancy of the colon. Colon is the part of the tube like organ or large intestine and the lower part of our digestive system that absorb nutrients and water, it stores solid waste (stool) that can be carried to the rectum and finally, expelled out from the body. Hence colon removes nutrients and fluids from the food we consume. The rectum is the last part of the large intestine where stool, the body’s waste product, is expelled through the anus.
Any ethnic or racial group may get effected from the colon cancer and often occur at the age of 50 or above, but now the younger people also getting colon cancer. Statics are increasing with the alarming rate, colon cancer is taking more than 50,000 lives every year and it is going to be 2nd leading cause of fatality.
The First sign of colon cancer is, it develops as a polyp, an abnormal growth inside rectum or colon, but may become malignant if not treated or removed surgically, mostly colon cancer is begin in the beginning and there is a knob like growth in the intestinal lining, sometimes with bleeding, blood in the stool and constipation and sometimes it develops without any significant symptoms.
Colon is a part of long intestine or large bowel, colorectal cancer or colon cancer arises in the colon or rectum that links colon and the anus. There may be many causes of colon cancer and they are not directly linked with the colon cancer, but if certain conditions such as inflammatory bowel disease, irritable bowel disease, intestinal infection and hemorrhoids and many more, if not treated completely may give rise to colon cancer, symptoms are undetectable and often appear after the cancer has reached at the advanced stage.
Some sign and symptoms of Colon Cancer are:
» Long term change in bowel habits, constipation or diarrhea for very long time span
» Bleeding in the rectum
» Blood in the stool or dark stool
» Abdominal pain and cramping
» Fatigue, weakness and drastic weight loss
It is better to visit the physician for the tests, if any above condition persists for the longer time. Early detection will help to prevent colon cancer by removing polyps or any abnormal cancerous growth and may save the life. Polyps can be detected by performing colonoscopy, some may be benign (non-cancerous) or some may be malignant (cancerous) polyps that can be removed by the surgery. Family history with colon cancer is the high risk factor in case of colon cancer, apart from consuming alcohol, smoking and obesity are other factors which may be the cause of colon cancer.
TOOLS TO DIAGNOSE THE COLON CANCER
» High-sensitivity fecal occult blood tests (FOBT) and the CBC: To check blood in the feces that is not seen visually.
» Stool DNA test: To detect tiny amounts of blood in the stool.
» Sigmoidoscopy: To see the colon linings and to remove the tissue for biopsy
» Colonoscopy (Optical or Standard): rectum or entire colon can be scanned to see any abnormal growth. » Virtual Colonoscopy (Computer tomography or CT scan): Uses special x-ray equipment (a CT scanner) This is less invasive method to detect the polyps and any other abnormalities.
» Double-contrast barium enema: To see the colon from outside or to see the growth of polyps outside the colon lining.
Conventional treatment of Colon Cancer:
Surgery is the first line treatment from starting to the end and chemotherapy is the adjuvant treatment and it may be given for the months to eradicate the tumor completely. Polyps at the affected area are removed through colonoscopy procedure, sometimes partial colostomy is done if the tumor is big enough and there is possibility that the person may require more than one surgery, depending on the severity and the stage of cancer.
Why turmeric for the Colon Cancer?
Chemotherapy for the colon cancer comes with severe side effects like, loosing hairs, vomiting and some time bed ridden this is not sound comfortable and compared to these unwanted effects plant based extract proven to be exceptionable safe and worthy without any serious downsides.
Turmeric is such type of natural medication which improves survival rate and provides protection without any downside; it works in colon cancer in many ways: » Curcumin targets the different pathways to kill the cancerous cells. It is known to cause cell death and induce apoptosis.
» Metastasis and proliferation are common phenomena in any cancer including colon cancer all these process makes the disease more worsening, curcumin targets the protein that are involved in both process and inhibit the cell cycle growth and in this way control the malignant cell growth in colon cancer.
» Curcumin suppresses the invasion or metastasis of the colorectal cancer cells as well and thus, prevents further spreading of cancerous cells.
» Curcumin also inhibits the specific gene expression, hence suppression the invasion of metastasis of cancer.
» Colon cancer is closely associated with inflammation, which encourages the invasion and the tumor growth so people with bowel disease inflammation are at great risk of getting colon cancer. Curcumin is already well known for its anti-inflammatory action with high therapeutic activity, which is most beneficial for the various inflammatory process involved in the colon cancer. Curcumin helps to suppress the inflammation and prevents the tumor development.
» Chemotherapeutic drugs sometimes do not respond to the tumor or show resistance due to some kind of mutation, curcumin has proven ability to reduce the drug induce resistance in colon cancer and at the same time increases the effectiveness of the medication.
» Curcumin enhances the sensitivity of tumor cells to the ongoing chemotherapy, even can sensitize the tumor cells and it can increase the effect of medication or it can synergizes the effect of the drugs. » Curcumin may overcome the drug induce toxicity due to its anti-oxidant and anti-inflammatory effect and protects the normal cells from further toxicity as well.
» Colon cancer is highly treatable if discovered timely, chemotherapy after surgical treatment is highly effective to improve and prolong the quality of life. Research on colon cancer is still continued to provide hope for the better treatment to combat the disease with less chemotherapy and surgeries.